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Biomedical Engineering Seminar Abstract
Fall 2007, October 22,

Mark Does Ph.D.
Assistant Professor, Biomedical Engineering, Radiology and Radiological Sciences, Vanderbilt University


“Tissue characterization with integrated diffusion-T2 measurements ”
-pdf

Abstract: Due to the microscopic compartition of water in tissue, water diffusion and NMR relaxation cannot generally be described by simple mono-exponential functions. In the context of MRI, each imaging voxel is not a homogeneous sample, but rather the integration of many micro-anatomical compartments. Diffusion weighted imaging is known to be particularly sensitive to the spatial dimensions of these compartments, but is not generally well suited to distinguishing signals from distinctly different compartments. Transverse relaxation, on the other hand, is well suited for such compartmental characterization in some tissues.  By combining diffusion and T2 weighting it is sometimes possible to estimate the apparent diffusion coefficient of water in multiple different micro-anatomical compartments within a given imaging voxel. Methods for such studies and their application to characterizing neural and muscle tissues will be presented.

Monday, October 22nd, 2007

2:00 pm – 3:00pm

Keating 103
Host:  Urs Utzinger, Ph.D. (626-9281)

Co-hosted with ARIBI

Persons with a disability may request a reasonable accommodation by contacting the Disability Resource Center at 621-3268 (V/TTY).  Requests should be made as early as possible to allow time to arrange the accommodation.