Optical Coherence Tomography: New Technology and Applications
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version of the abstract
Abstract
Optical coherence tomography (OCT) is an optical analogue of ultrasound,
using reflected near-infrared light waves to non-destructively
image tissue. A resolution of 2-20 µm and imaging depth
of 1-2 mm are obtainable in most biological tissues. Technology
for OCT is still in the developmental stages; we are working on
novel endoscopic probes, signal processing, and contrast agents.
While it was recognized early on that OCT offered an unprecedented
opportunity for retinal imaging, other optimal applications are
still being sought. We have shown that OCT is ideal for imaging
of precancers and tumor development human and mouse skin, ovary,
and colon.
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