"Vascular Research: A Perspective from the Jersey Shore"
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From custom stent-grafts to the remodeling response evoked by stent forces, vascular mechanics drives device design. By understanding vessel wall constituent contributions and developing relatively simple models, the engineer can assist clinicians in understanding the design process. In addition, our investigations elucidate the mechanisms of blood vessel adaptation and contribute to basic science research. This presentation covers the stent-graft project at The Robert Wood Johnson University Hospital (New Brunswick, NJ), the development of a group of models explaining various aspects of vascular stress-strain curves, and a preliminary model of blood vessel remodeling behavior.